May 12

There’s a delightful story that does the rounds regarding one of the founding fathers of Linux. It’s said that during the early days of the open-
source operating system’s development, this fellow took to attending conferences in complete silence. All attempts to communicate via means other than hand gestures were refused. Instead, he pointed at things.

Apocryphal or not, the tale remains highly relevant today. Our hero’s beef was with the windows-based graphical interface metaphor and its knack for turning us into mouse-pointing morons. Fast-forward a decade or two and astonishingly little has changed. The windows GUI has, you might say, proven to be extremely gluey.

The classic case study is Microsoft’s eponymous Windows OS. Admittedly, early versions of Windows would seem pretty alien to today’s users – but that’s an illusion. Look past the clunky graphics and Windows 95 is largely identical even to Windows 7, Redmond’s latest and greatest OS. Icons, taskbar, the folder metaphor – all are essentially the same as they were 15 years ago.

That’s a long time in any industry, but it’s an absolute eternity in information technology. Along the way, Microsoft has flirted with a few interesting new features. Early betas of Vista included widespread use of virtual folders and the promise of a fully vectorised and hence scalable graphical interface, for instance. But in the end, the retail build of Vista was yet another reskin of Windows NT, just a bit prettier.

Linux and Apple’s Macintosh operating systems have scarcely been any more innovative. More user-friendly and configurable? Perhaps. More polished? Certainly. But both remain firmly rooted in the window-juggling keyboard-and-mouse camp.

Compared to the enormous advances made in computer hardware, it’s all a bit bizarre. Back in 1995, a single-core Pentium processor running at 100MHz or so was your lot. That’s an in-order 3.1 million transistor chip with 8kB of cache memory, for goodness sake. Today, we’re up to six cores, multiple GHz, over a billion transistors and cache pools nigh on double-digits in MB.

If you think that’s merely a matter of scale rather than a new paradigm per se, what about features such as virtualisation or hardware-accelerated 3D graphics? That’s to say nothing of the rapid rise of LCD monitors and more recently solid-state drives. By any sane metric, computer hardware has been in a constant state of revolution. It’s utterly relentless.

So, not to put too fine a point on it, what gives with GUIs? The answer, frankly, is that I don’t know. Over the years, I’ve visited several labs dedicated to advanced interface research, including those of Microsoft and Intel. I’ve even interviewed luminaries from the heyday of interface research, including some who worked at the fabled Xerox PARC lab in Palo Alto. The very people who invented the GUI, in other words. In fact, I reckon I’ve spoken to all the right people. I’ve played with all the latest table-top, touchscreen human-machine interfaces. But I remain essentially clueless. Nothing I’ve seen or heard of is obviously the next big thing.

At this point, Apple’s iPad inevitably hovers into view. A remarkable device in many ways, it’s no good for data input or content creation and therefore doesn’t offer a plausible alternative for desktop computing. However, what it does is underline just how painful the Windows interface is. Once you’ve danced around a few of your favourite websites courtesy of the iPad’s delightfully responsive screen, the scrolly-scrolly, pointy-clicky PC experience seems pretty laughable.

Even a good smartphone can make the PC feel clumsy; I often prefer reading emails on mine. Replying to them is out of the question, but as a viewing device it’s very pleasant and provides temporary relief from what is becoming an overly familiar and oppressive desktop computing experience. You could say the differences are largely arbitrary, but trawling emails on my phone feels like a break from work. That’s got to say something about the tiredness of the windows metaphor.

Apr 27

Electronic Data Capture (Edc) By: KunalHanda


A pharmaceutical company or sponsor may have particular interest; research and academic institute may have another. Whatever may be the case; the major role of clinical data management is collection of clinical trial data and ensures that data is error free, consistent and complete. Data is generated at the clinical trial site and stored in paper form and more recently in EDC (electronic data capture).


The site is usually a hospital/clinic where the patients in the clinical trial are recruited and provided the drug treatment as per a well-defined protocol. There are many guidelines and also laws that outline the governance and conduct of the trial to ensure the safety of the patients involved. The clinical trial data gathered at the investigator site in the case report form (CRF) is transcripted in the clinical data management system (CDMS).


Some of the popular platforms used globally are Oracle Clinical and Clintrial. The EDC platforms wherein the data is entered directly into the system at the site include Inform, Medidata and Oracle Clinical. To reduce the possibility of errors due to human entry, the system employs the double data entry to ensure high quality of data in paper-based trials. Once the data has been screened for typographical errors, the data is validated to check for logical errors. The entered data is cleaned, reviewed, extracted and provided to the biostatisticians for review.


At the end of the clinical trial, the data in the CDMS is analyzed and sent to the regulatory authorities for approval. Electronic Data Capture- The Future Globally, we are observing a shift from the traditional paper-based study to electronic version, commonly termed as EDC ,electronic data capture. The major reason for this can be attributed to the growth in Information Technology (IT) service sector for Life Sciences. EDC has not only made easier to capture data remotely from various sites but also with inbuilt validation and edit checks it has made possible to collect error free data in the very first stage. EDC systems have also made handling of clinical trial data more secure and efficient. The data from the EDC systems can be exported in various formats like CDISC, XML, etc.


With tremendous growth in storage technologies (SAN, NAS), it has become a reality to store terabytes of EDC trail data in a small space securely and in a cost effective way compared to storing large volume of paper documents during traditional paper trials. Earlier the time required to clean trial data was quite high compared to the trial data in EDC. As the volume of information collected in clinical trials continues to grow, data collection and management is becoming a priority for pharmaceutical companies and clinical research organizations. One of the critical component in clinical trials is Capturing data which is more accurate and in time to market for potential new drugs.Electronic data capture (EDC) systems are used in all phases of clinical trials to collect, manage, and report clinical and laboratory data. Electronic data capture (EDC) provides both the tools and the process infrastructure necessary to achieve the needed data quality as well as process scalability.


About the Author

MakroCare, a multidisciplinary knowledge and technology driven clinical research organization (CRO) that offers CDM (paper and Electronic) and EDC Services and many more. It does the data analyses, reporting and submission of trial data to the regulatory agencies in much fast pace thereby saving precious time and cost.
Article Source: http://www.articlesbase.com/

Mar 05

Importance of outsourcing data entry work has increased nowadays as the highly cutthroat business scenario poses various challenges before corporate, small and large business firms, banks, insurance companies, healthcare organizations, publishers and educational institutions. There are number of data entry companies that provide cost-effective and systematic data entry services all around the world as any company would want to try their best to save on costs and expenses. Companies make many short and long-term plans, and adopt wisdom help them decrease their spending.

However, the best step a company management can take in order to save on spending is to outsource their business What is Outsourcing? In simple terms, outsourcing is done when a particular company establishes a contract with another agency or company to get some of its work done, which otherwise is supposed to be done by the primary company itself. The contracting agencies and companies to whom work is handed over are a specialist is the field which the contract received is related to.

During these days a majority of multinational companies are outsourcing jobs and tasks regarding customer services and call center, marketing, online businesses, medical transcription, payroll management, etc. Typically, companies search for outsourcing agencies which belong to other countries. This is done to save costs considerably by paying the outsourcing agencies of other countries less than what is to be paid for the same task if done by an agency of the same country.

When to Consider Outsourcing Your Business? The management of a company needs to consider on some points which may help them to decide if they should really outsource the jobs. The management should make sure that the tasks which are to be outsourced are not the primary income generating tasks.

Generally, companies choose to outsource jobs that are of less value and do not contribute much in revenue generations. If any task has become a routine and is consuming handsome amount of time and energy of in-house employees, such a task is appropriate of being outsourced. The tasks that are supportive in nature and are as well boring, such tasks can also be outsourced. For example, a company who has very less to do with Information Technology would only think how to outsource IT. Hopefully, by now you might have got a fair idea on how to outsource your business effectively.

Finding out what needs to be outsourced and choosing an appropriate outsourcing agency is what is required to lessen the unnecessary costs of your company, thus increasing profits. For more information visit: Tricon Solutions & Services Home Based Jobs.

About the Author
Paul Williams is the director of Tricon Solutions & Services Home Based Jobs Work From Home Jobs Data Entry Job , {a href= http://www.triconsol.com/services.php} Data Entry Jobs & Work At Home , {a href= http://www.triconsol.com/registration.php} Join Now – Data Entry Jobs . He has 20 years of experience in the marketing and E-commerce industries and has been helping jobless and startup.

Article Source: http://www.goarticles.com/